Cancer Weekly
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Adenocarcinoma
Studies from National Taiwan University, Medical Department yield new data on adenocarcinoma
December 23rd, 2008
According to a study from Taipei, Taiwan, "Cadherin-17, also called liver-intestine cadherin, is a calcium-dependent transmembrane glycoprotein that mediates cell -cell adhesion in intestinal epithelium. Expression of cadherin-17 was reported in gastric, pancreatic, and colorectal adenocarcinomas but not in other tumors." "Whether cadherin-17 can be used as a marker for diagnosis of cancers is still unclear. In this study, we used immunohistochemical methods to stain cadherin-17 in tissue arrays containing most normal tissues and 518 carcinomas from many anatomic sites. Among normal tissues, the expression of cadherin-17 was limited to epithelial cells of small...
Source: Cancer Weekly (2008-12-23)
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