Cancer Weekly
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Apoptosis
Researchers' work from Queen's University focuses on apoptosis
December 23rd, 2008
According to recent research from North Ireland, "We have developed a versatile and rapid method for the quantitative estimation of cell death kinetics, following direct single-shot activation of the mitochondrial death pathway by a cell permeable BH3 activator peptide (D-R(8)BH3(BID)). This approach employs timelapse epifluorescent imaging of live cells and a machine- vision based feature extraction algorithm, to measure unidirectional stochastic transitions associated with mitochondrial inner membrane potential depolarization and/or permeability transition, at single cell resolution." "This data is transformed to enable construction of a right step-wise survival...
Source: Cancer Weekly (2008-12-23)
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