Cancer Weekly
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DNA Vaccines
Study results from P. Chiarella et al provide new insights into DNA vaccines
December 23rd, 2008
According to recent research from Rome, Italy, "Plasmid DNA vaccination combined with electroporation (EP) provides a promising approach for the prevention of infectious diseases and for cancer immunotherapy. This technology has been described as being effective in activating humoural and cellular immune response in the host as well as in enhancing expression of the encoded antigen." "Several reports showed EP has adjuvant-like properties when combined with plasmid DNA injection although the effect in the absence of DNA has not been investigated. The aim of this study is to clarify whether the application of EP alone to the skeletal muscle is able to recruit and trigger...
Source: Cancer Weekly (2008-12-23)
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