Cancer Weekly
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Cancer Gene Therapy
Researchers from University of Alabama describe findings in cancer gene therapy
December 30th, 2008
According to a study from the United States, "Cell-based therapy for cancer is a promising new field. Among cell types that can be used for this purpose, mesenchymal stem cells (MSCs) appear to hold great advantage for reasons including easier propagation in culture, possible genetic modification to express therapeutic proteins and preferential homing to sites of cancer growth upon in vivo transfer." "The present study evaluated the potential of genetically modified MSC, constitutively expressing interferon (IFN)-beta, in an immunocompetent mouse model of prostate cancer lung metastasis. A recombinant adeno-associated virus (rAAV) encoding mouse IFN-beta was constructed...
Source: Cancer Weekly (2008-12-30)
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