Cancer Weekly
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Human Papillomavirus
Data from P. Lenzi and colleagues advance knowledge in human papillomavirus
December 30th, 2008
According to recent research published in the journal Transgenic Research, "Human Papillomavirus (HPV) is the causal agent of cervical cancer, one of the most common causes of death for women. The major capsid L1 protein self-assembles in Virus Like Particles (VLPs), which are highly immunogenic and suitable for vaccine production." "In this study, a plastid transformation approach was assessed in order to produce a plant-based HPV-16 L1 vaccine. Transplastomic plants were obtained after transformation with vectors carrying a chimeric gene encoding the L1 protein either as the native viral (L1(v) gene) or a synthetic sequence optimized for expression in plant...
Source: Cancer Weekly (2008-12-30)
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