Cancer Weekly
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Cancer Vaccines
Data on cancer vaccines described by researchers at New York University, Cancer Institute
December 30th, 2008
Investigators publish new data in the report 'KBMA Listeria monocytogenes is an effective vector for DC-mediated induction of antitumor immunity.' "Vaccine strategies that utilize human DCs to enhance antitumor immunity have yet to realize their full potential. Approaches that optimally target a spectrum of antigens to DCs are urgently needed," scientists in the United States report. "Here we report the development of a platform for loading DCs with antigen. It is based on killed but metabolically active (KBMA) recombinant Listeria monocytogenes and facilitates both antigen delivery and maturation of human DCs. Highly attenuated KBMA L. monocytogenes were...
Source: Cancer Weekly (2008-12-30)
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