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Gene Therapy
Hoshi University, Institute of Medicinal Chemistry describes research in gene therapy
December 30th, 2008
Fresh data on gene therapy are presented in the report 'Folate-linked lipid-based nanoparticles for synthetic siRNA delivery in KB tumor xenografts.' According to recent research from Tokyo, Japan, "RNA interference (RNAi) is a sequence-specific gene-silencing mechanism triggered by synthetic small interfering RNA (siRNA), and is utilized in a wide range of fields including cancer gene therapy by down-regulating a specific target protein. In this study, for tumor-targeted siRNA delivery, we developed a folate-linked nanoparticle (NP-F), and evaluated the potential of NP-F-mediated tumor gene therapy in human nasopharyngeal KB cells, which overexpressed folate receptor (FR)."...
Source: Cancer Weekly (2008-12-30)
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