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Gene Therapy
Hoshi University, Institute of Medicinal Chemistry details research in gene therapy
December 30th, 2008
A report, 'NaCl induced high cationic hydroxyethylated cholesterol-based nanoparticle-mediated synthetic small interfering RNA transfer into prostate carcinoma PC-3 cells,' is newly published data in Biological and Pharmaceutical Bulletin. "The RNA interference (RNAi) effect is an alternative technology to antisense DNA as an experimental method of down-regulating a specific target protein. Optimal gene therapy for tumors must deliver synthetic small interfering RNA (siRNA) to tumor cells with high efficiency and minimal toxicity," researchers in Tokyo, Japan report. "Previously, we reported that cationic nanoparticles composed of...
Source: Cancer Weekly (2008-12-30)
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