Renal Cell Carcinoma

Researchers at Medical University of Vienna target renal cell carcinoma

Published in Cancer Weekly, December 30th, 2008

According to a study from Vienna, Austria, " Sunitinib and sorafenib are tyrosine kinase inhibitors (TKIs) that have considerable efficacy in metastatic renal cell carcinoma. TKI-associated cardiotoxicity was reported in approximately 10% of the patients."

"Detailed cardiovascular monitoring during TKI treatment may reveal early signs of myocardial damage. Patients and Methods In this observational, single-center study, all patients intended for TKI treatment were analyzed for coronary artery disease (CAD) risk factors, history or evidence of CAD, hypertension, rhythm disturbances, and heart failure. Monitoring included assessment of symptoms, ECGs, and biochemical...

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Source: Cancer Weekly (2008-12-30)

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