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Angiogenesis
Reports from Central South University advance knowledge in angiogenesis
December 30th, 2008
"The angiogenesis induced by tumor cells is essential for metastasis of hepatocellular carcinoma. Available information suggests that RhoC participates in angiogenesis through regulation of vascular endothelial growth factor expression in tumor cells," researchers in Changsha, People's Republic of China report. "For its broad functions in cell migration and cytoskeletal organization, we hypothesized that RhoC regulating angiogenesis does not exclusively depend on regulation of vascular endothelial growth factor expression. To address this question, in the present study, we used a retroviral small interfering RNA approach to selectively knockdown the expression of RhoC...
Source: Cancer Weekly (2008-12-30)
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