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Ovarian Cancer Epidemiology

Studies from University of North Carolina, Department of Epidemiology have provided new data on ovarian cancer epidemiology

Published in Cancer Weekly, December 30th, 2008

Investigators publish new data in the report 'Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.' "Over 22,000 cases of ovarian cancer were diagnosed in 2007 in the United States, but only a fraction of them can be attributed to mutations in highly penetrant genes such as BRCA1. To determine whether low-penetrance genetic variants contribute to ovarian cancer risk, we genotyped 1,536 single nucleotide polymorphisms (SNP) in several candidate gene pathways in 848 epithelial ovarian cancer cases and 798 controls in the North Carolina Ovarian Cancer Study (NCO) using a customized Illumina array," scientists in the United States report.

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