Cancer Weekly
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Stem Cell Research
New stem cell research study findings have been reported from University of Munich
January 6th, 2009
According to recent research from Munich, Germany, "Genomic integration by the Streptomyces bacteriophage phi C31 integrase is a promising tool for non-viral gene therapy of various genetic disorders. We investigated the phi C31 integrase recombination activity in T cell derived cell lines, primary T lymphocytes and CD34(+) haematopoietic stem cells in comparison to mesenchymal stem cells and cell lines derived from lung-, liver- and cervix-tissue." "In T cell lines, enhanced long-term expression above control was observed only with high amounts of integrase mRNA. Transfections of phi C31 integrase plasmids were not capable of mediating enhanced long-term transgene...
Source: Cancer Weekly (2009-01-06)
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