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Cancer Weekly

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Cancer Gene Therapy



Research from University of Sydney, Department of Surgery in the area of cancer gene therapy published



January 6th, 2009

Fresh data on cancer gene therapy are presented in the report 'Cytosolic phospholipase A2-alpha: a potential therapeutic target for prostate cancer.' "Cytosolic phospholipase A2-alpha (cPLA2-alpha) provides intracellular arachidonic acid to supply both cyclooxygenase and lipoxygenase pathways. We aim to determine the expression and activation of cPLA2-alpha in prostate cancer cell lines and tissue and the effect of targeting cPLA2-alpha in vitro and in vivo," scientists writing in the journal Clinical Cancer Research report.

"The expression of cPLA2-alpha was determined in prostate cancer cells by reverse transcription-PCR, Western blot, and immunocytochemistry....


Source: Cancer Weekly (2009-01-06)

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