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Cancer Weekly

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Cancer Therapy Vaccines



Researchers from Medical University of Vienna report on findings in cancer therapy vaccines



January 6th, 2009

Researchers detail in 'Reduction of human melanoma tumor growth in severe combined immunodeficient mice by passive transfer of antibodies induced by a high molecular weight melanoma-associated antigen mimotope vaccine,' new data in cancer therapy. "The high molecular weight melanoma-associated antigen (HMW-MAA) is an attractive target for immunotherapy of malignant melanoma. We have recently generated a vaccine based on the HMW-MAA mimotope 225D9.2+ that was able to induce anti-HMW-MAA antibodies with antitumor activity in vitro," scientists in Vienna, Austria report.

"Here, we investigated the antitumor activity of these antibodies in a human melanoma xenotransplant...


Source: Cancer Weekly (2009-01-06)

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