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Breast Cancer

Data on breast cancer reported by K. Yalamanchili and co-researchers

Published in Cancer Weekly, January 6th, 2009

"Despite the advances in breast cancer care, inflammatory breast cancer (IBC) has a poor prognosis. The purpose of this study was to determine the efficacy of high-dose chemotherapy (HDCT) with thiotepa, mitoxantrone and carboplatin (TMJ regimen) in women with TNM stage IIIB IBC," scientists in the United States report.

"Between 1991 and 1998, twenty-eight patients with stage IIIB IBC underwent an autologous stem cell transplant after undergoing chemotherapy, surgery and/or radiation. Stem cells were collected from the bone marrow and periphery after mobilization with growth factors. Patients received thiotepa 250 mg/m(2) once daily i.v. for 3 days, mitoxantrone 40...

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