Cancer Weekly
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Cancer Vaccines
Research from A. Vigil and co-authors in the area of cancer vaccines published
January 6th, 2009
According to recent research from the United States, "Naturally occurring strains of Newcastle disease virus (NDV) are currently being investigated in multiple clinical trials for oncolytic cancer therapy in the United States and abroad. We have previously reported, for the first time, the development of recombinant NDVs designed for enhanced cancer therapeutic efficacy." "Specifically, we have shown that NDV engineered to express interleukin-2 (IL-2) generates a robust therapeutic response associated with increased tumor-specific T-cell infiltration after intratumoral administration in mice. We have now demonstrated that this therapeutic response is dependent on T...
Source: Cancer Weekly (2009-01-06)
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