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Cancer Gene Therapy
New cancer gene therapy research reported from Tokyo Dental College, Department of Pathology
January 13th, 2009
Research findings, 'Inhibition of syndecan-1 expression and function in oral cancer cells,' are discussed in a new report. According to a study from Chiba, Japan, "Syndecan-1 has been shown to be a prognostic factor in various types of tumors, suggesting its correlation with malignancy and metastasis. In the present study, we examined the expression of syndecan-1 in oral cancer cell lines and tested whether transfection of an siRNA against human syndecan-1 affected the malignant potential of these cells." "Seven different human oral cancer cell lines (HSC2, HSC3, HSC4, Ca9-22, SAS, KB and BSC-OF) were used. To evaluate the mRNA expression of syndecan-1 in these cell...
Source: Cancer Weekly (2009-01-13)
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