Cancer Weekly
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Bladder Cancer
Researchers from Radboud University publish findings in bladder cancer
January 13th, 2009
"First degree relatives of patients with bladder cancer have a two-fold increased risk of bladder cancer but high-risk bladder cancer families are extremely rare. There is no clear Mendelian inheritance pattern that can explain the increased familial risk," scientists in Netherlands report. "This makes classical linkage studies for the mapping of susceptibility genes impossible. The disease is probably caused by a combination of exposure to exogenous carcinogens and a large number of susceptibility genes with modest effects. Genome-wide association studies are better suited to identify these genes," wrote L.A.L.M. Kiemeney and colleagues, Radboud University. ...
Source: Cancer Weekly (2009-01-13)
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