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Oral Squamous Cell Carcinoma Immunology

Researchers at National Health Research Institutes target oral squamous cell carcinoma immunology

Published in Cancer Weekly, January 13th, 2009

Research findings, 'The involvement of promoter methylation and DNA methyltransferase-1 in the regulation of EpCAM expression in oral squamous cell carcinoma,' are discussed in a new report. According to recent research from Miaoli, Taiwan, "Epithelial cell adhesion molecule (EpCAM) is important for cell proliferation and differentiation but mechanisms regulating their expression are unclear. Because EpCAM may play a role in carcinogenesis, we investigated the clinicopathologic significance of its expression in oral squamous cell carcinoma (OSCC) and the involvement of DNA methylation machinery in regulation of EpCAM expression during tumorigenesis."

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