Breast Cancer

Researchers at University of Queensland have published new data on breast cancer

Published in Cancer Weekly, January 13th, 2009

According to recent research published in the journal Cancer Research, "BRCA1 is a breast cancer susceptibility gene that is down-regulated in a significant proportion of sporadic breast cancers. BRCA1 is posttranscriptionally regulated by RNA-binding proteins, the identities of which are unknown."

"HuR is an RNA binding protein implicated in posttranscriptional regulation of many genes and is overexpressed in sporadic breast cancer. To investigate the possibility that these two molecules are functionally linked in breast cancer, we performed bioinformatic analysis of the BRCA1 3' untranslated region (UTR), RNA-protein assays with the HuR protein and the BRCA1...

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Source: Cancer Weekly (2009-01-13)

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