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Cancer Weekly

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Cancer Gene Therapy



New cancer gene therapy data have been reported by scientists at Kyoto Prefectural University, Department of Molecular



January 20th, 2009

New research, 'Anti-gout agent allopurinol exerts cytotoxicity to human hormone-refractory prostate cancer cells in combination with tumor necrosis factor-related apoptosis-inducing ligand,' is the subject of a report. According to a study from Kyoto, Japan, "Allopurinol has been used for the treatment of gout and conditions associated with hyperuricemia for several decades. We explored the potential of allopurinol on cancer treatment."

"Allopurinol did not expose cytotoxicity as a single treatment in human hormone refractory prostate cancer cell lines, PC-3 and DU145. However, allopurinol drastically induced apoptosis of PC-3 and DU145 in combination with tumor...


Source: Cancer Weekly (2009-01-20)

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