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Cancer Weekly

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Vaccines



Korea University describes research in vaccines



January 20th, 2009

Fresh data on vaccines are presented in the report 'Gene transfer of AIMP1 and B7.1 into epitope-loaded, fibroblasts induces tumor-specific CTL immunity, and prolongs the survival period of tumor-bearing mice.' According to recent research from Seoul, Korea, "T helper type 1 (Th1) cell-mediated immune responses play various roles in cellular immunity, including inducing cytotoxic T lymphocytes (CTLs) and they have been shown to be crucial in cancer immunotherapy. Previously, we found that aminoacyl-tRNA synthetase-interacting multifunctional protein 1 (AIMP1) stimulated antigen-presenting cells to secrete IL-12, leading to enhanced Th1 cell responses."

"In this study,...


Source: Cancer Weekly (2009-01-20)

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