Cloning
Scientists at University of Southampton publish research in cloning
Published in Cancer Weekly, January 20th, 2009
"The search for target genes involved in unbalanced acquired chromosomal abnormalities has been largely unsuccessful, because the breakpoints of these rearrangements are too variable. Here, we use the example of dicentric chromosomes in 8 cell precursor acute lymphoblastic leukemia to show that, despite this heterogeneity, single genes are targeted through a variety of mechanisms," scientists writing in the journal Proceedings of the National Academy of Sciences of the United States of America report.
"FISH showed that, although they were heterogeneous, breakpoints on 9p resulted in the partial or complete deletion of PAX5. Molecular copy number counting further...
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Source: Cancer Weekly (2009-01-20)
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