Cancer Weekly
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Adrenocortical Cancer
Data on adrenocortical cancer published by researchers at University of Marburg
January 20th, 2009
According to recent research from Marburg, Germany, "In this study, we evaluate whether Snail is expressed in adrenocortical cancer (ACC) and if its expression is related to patient outcome. One of the best known functions of the zinc-finger transcription factor Snail is to induce epithelial-to-mesenchymal transition (EMT)." "Increasing evidence suggests that EMT plays a pivotal role in tumour progression and metastatic spread. Snail and E-cadherin expression were assessed by immunohistochemistry in 26 resected ACCs and real-time quantitative RT-PCR expression analysis was performed. Data were correlated with clinical outcome and in particular with overall patient...
Source: Cancer Weekly (2009-01-20)
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