Cancer Weekly
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Angiogenesis
Reports outline angiogenesis research from Stanford University, Medical Department
January 20th, 2009
According to a study from the United States, "Glioblasomta multiforme (GBM) is a WHO grade IV malignant brain tumor with poor prognosis, despite advances in surgical and adjuvant therapy. GBM is characterized by areas of central necrosis and high levels of angiogenesis, during which increased vascular permeability allows for the extravasation of endothelial progenitor cells to support blood vessel and tumor growth." "The purpose of this study was to characterize changes in tumor vascular permeability, vascular density and vessel morphology in vivo during angiogenesis. An orthotropic murine (GL26) glioblastoma model was used in this study. In vivo serial dynamic...
Source: Cancer Weekly (2009-01-20)
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