Cancer Weekly
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Angiogenesis
Researchers at Yonsei University, Medical Department publish new data on angiogenesis
January 20th, 2009
"The plant sterol guggulsterone has been shown to exert anti-tumor effects, making it a candidate chemotherapeutic agent. We investigated the anti-tumor effects of guggulsterone on colon cancer cells and elucidated the underlying molecular mechanisms related to angiogenesis," scientists in Seoul, South Korea report. "The apoptotic effects of guggulsterone were examined by cell survival assay. Western blot analysis was used to determine the levels of various down-stream intracellular proteins involved in angiogenesis, including signal transducer and activator of transcription 3 (STAT3), vascular endothelial growth factor (VEGF), hypoxia-inducible factor-1 alpha (HIF-1...
Source: Cancer Weekly (2009-01-20)
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