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Cancer Weekly

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Angiogenesis



Researchers from Annamalai University describe findings in angiogenesis



January 20th, 2009

"We investigated the combinatorial chemopreventive efficacy of Azadirachta indica (AI) and Ocimum sanctum (OS) against N-methyl-N'- nitro-N-nitrosoguanidine (MNNG)-induced gastric carcinogenesis, based on changes in oxidant-antioxidant status, cell proliferation, apoptosis and angiogenesis. Male Wistar rats were assigned to four groups," scientists writing in the Singapore Medical Journal report.

"Rats in groups 1 and 2 received MNNG ( 150 mg/kg body weight i.g.) three times with a gap of two weeks in between the treatment. Group 2 rats additionally received ethanolic AI ( 100 mg/kg body weight i.g.) and OS ( 150 mg/kg body weight i.g.) leaf extract three times...


Source: Cancer Weekly (2009-01-20)

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