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Cancer Weekly

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Apoptosis



Research on apoptosis published by scientists at Xiamen University



January 20th, 2009

According to recent research published in the journal Carcinogenesis, "Acutely transforming retrovirus AKT8 in rodent T cell lymphoma (Akt) phosphorylates and regulates the function of many cellular proteins involved in processes such as metabolism, apoptosis and proliferation. However, the precise mechanisms by which Akt promotes cell survival and inhibits apoptosis have been characterized in part only."

"TR3, an orphan receptor, functions as a transcription factor that can both positively or negatively regulate gene expression. We have reported previously that the translocation of TR3 from the nucleus to the mitochondria can elicit a proapoptotic effect in...


Source: Cancer Weekly (2009-01-20)

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