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Cancer Weekly

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Apoptosis



Researchers from Shu-Te University describe findings in apoptosis



January 20th, 2009

"Areca nut (AN) is recognized as a human carcinogen; however, few studies of the cytotoxic effects of AN ingredients on cells have been reported. In Taiwan, AN, lime and inflorescence of Piper betle are the common components of betel quid (BQ)," researchers in Taiwan report.

"We recently noticed that extract of AN (ANE), but not those of lime and inflorescence of Piper betle, induces rounding cell morphology and nuclear shrinkage in different types of carcinoma cells. In this study, the rounding cell activity was first traced to the partially purified >= 10 kDa fraction (ANE >= 10 K) and subsequently to the 30-100 kDa fraction (ANE 30-100 K). ANE and ANE >= 10...


Source: Cancer Weekly (2009-01-20)

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