Cancer Gene Therapy

New cancer gene therapy data have been reported by H.J. Wu and co-authors

Published in Cancer Weekly, January 20th, 2009

According to a study from Wuhan, People's Republic of China, "PTEN (phosphatase and tensin homologue deleted on chromosome 10) is a tumor suppressor gene identified on human chromosome 10q23. Substantial studies have demonstrated that PTEN can inhibit cell proliferation, migration and invasion of many cancer cells."

"The purpose of this study was to determine whether upregulation of PTEN gene by transfection wild-type PTEN gene to ovarian cancer cells can inhibit growth and migration and to explore the potential for PTEN gene therapy of ovarian cancers. Wild-type and phosphatase-inactive (C124A) PTEN plasmids were transfected into ovarian epithelial cancer A2780 cells,...

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Source: Cancer Weekly (2009-01-20)

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