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Cancer Weekly

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Ovarian Cancer



First Patient Dosed in Phase 2 Clinical Trial of NKTR-102 in Ovarian Cancer



January 27th, 2009

Nektar Therapeutics (NASDAQ:NKTR) announced that dosing has started in a Phase 2 clinical trial of NKTR-102 in platinum-resistant ovarian cancer. Regulatory approvals have also been obtained and dosing will begin shortly in two additional trials: a randomized Phase 2 study to evaluate NKTR-102 versus irinotecan in second-line colorectal cancer patients with the KRAS gene mutation, and a Phase 2 study in metastatic breast cancer. Nektar has also received Institutional Review Board (IRB) approval for a Phase 2 cervical cancer study of NKTR-102.

"NKTR-102 is an excellent example of how Nektar's advanced polymer conjugate technology platform allowed us to precisely modify a...


Source: Cancer Weekly (2009-01-27)

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