Published in Cancer Weekly, January 27th, 2009
"The molecular mechanisms in myeloproliferative disorders that prevent apoptosis induced by damaged DNA are obscure. We searched for abnormalities of the proapoptotic Bcl-x(L) deamidation pathway in primary cells from patients with chronic myeloid leukemia (CML) or polycythemia vera, myeloproliferative disorders associated with the BCR-ABL fusion kinase and the Janus tyrosine kinase 2...
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