Osteosarcoma
Data on osteosarcoma published by researchers at Masaryk University
Published in Cancer Weekly, January 27th, 2009
"Nestin was originally identified as a class VI intermediate filament protein that is expressed in stem cells and progenitor cells in the mammalian CNS during development. This protein is replaced in the adult organism by other intermediate filament proteins; however, nestin may be re-expressed under certain pathological conditions such as ischemia, inflammation, brain injury, and neoplastic transformation," scientists in Brno, Czech Republic report.
"Nestin has been detected in many kinds of tumors, especially in tumors derived from the CNS. Co-expression of nestin and the CD133 surface molecule is considered to be a marker for cancer stem cells in neurogenic tumors....
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Source: Cancer Weekly (2009-01-27)
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