Cancer Weekly
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Adenoma
Study results from Cleveland Clinic update understanding of adenoma
January 27th, 2009
"Context.-Immunohistochemical stains for androgen receptor (AR), HER-2/neu, and p53 are used as diagnostic markers associated with malignancy in several histologic types of salivary gland tumors. These markers may be useful in differentiating pleomorphic adenoma with cytologic atypia from intracapsular carcinoma ex pleomorphic adenoma (CXPA), as these tumors are often difficult to distinguish on the basis of morphology alone," scientists in the United States report. "Objective.-To determine whether AR, HER-2/neu, and p53 expression can be seen in entirely benign pleomorphic adenomas. Design.-Androgen receptor, HER-2/neu, and p53 immunoreactivity was assessed in 41...
Source: Cancer Weekly (2009-01-27)
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