Cancer Weekly
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Apoptosis
Reports on apoptosis findings from W. Li and co-researchers provide new insights
January 27th, 2009
According to recent research from the United States, "Two types of interferons (IFNs), type I (IFN-alpha/beta) and type III (IFN-lambda s), utilize distinct receptor complexes to induce similar signalling and biological activities, including recently demonstrated for IFN-lambda s antitumour activity. However, ability of type III IFNs to regulate cell population growth remains largely uncharacterized.Materials and methods: Intact and modified human colorectal adenocarcinoma HT29 cells were used to study regulation of apoptosis by IFN-lambda s. We report that the IFN-lambda R1 chain of the type III IFN receptor complex possesses an intrinsic ability to trigger apoptosis in cells."...
Source: Cancer Weekly (2009-01-27)
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