Cancer Weekly
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Autoimmune Pancreatitis
Research from Massachusetts General Hospital provides new data about autoimmune pancreatitis
January 27th, 2009
"Autoimmune pancreatitis (AIP) shows a unique spectrum of histologic features and commonly presents with an abundant IgG4-positive (IgG4+) plasma cell infiltration. However, differentiating AIP from other mass lesions, particularly pancreatic cancer [invasive ductal carcinoma (IDC)] can be clinically challenging," scientists writing in the American Journal of Surgical Pathology report. "In this study, we evaluated the validity of IgG4 and IgG immunohistochemistry of ampullary and periampullary tissue for the diagnosis of AIR Our study group consisted of 14 resected AIP cases with appropriate ampullary sections. Superficial ampullary tissue and ''shouldering''...
Source: Cancer Weekly (2009-01-27)
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