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Hepatitis C Virus Therapy

New hepatitis C virus therapy research from University of Cologne, Institute for Pathology outlined

Published in Cancer Weekly, January 27th, 2009

Investigators publish new data in the report 'Adiponectin inhibits steatotic CD95/Fas up-regulation by hepatocytes: therapeutic implications for hepatitis C.' "Steatosis may trigger hepatocytes to up-regulate CD95/Fas thereby increasing susceptibility to apoptosis, inflammation and fibrosis. We investigated this concept and potential roles of adiponectin and its receptors (AdipoR1; AdipoR2) in chronically HCV-infected patients," scientists in Cologne, Germany report.

"In 98 HCV+ patients and 20 controls, sera were tested for HCV genotypes, FFAs, adiponectin and the M30 apoptosis indicator, and biopsies were evaluated for steatosis/inflammation/fibrosis, CD95/Fas...

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