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Cancer Weekly

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Cancer Vaccines



Research from University of California provides new data on cancer vaccines



February 3rd, 2009

According to a study from the United States, "Testing immunotherapeutic strategies for prostate cancer has been impeded by the lack of relevant tumor models in immunocompetent animals. This opportunity is now provided by the recent development of prostate specific PTEN knockout mice, which show spontaneous development of true adenocarcinoma arising from prostate epithelium and more faithfully recapitulate the human disease than any previous model."

"We investigated the feasibility of using tumor cells derived from this model to test tumor vaccination and adoptive immunotherapeutic strategies for prostate cancer. PTEN-CaP8 adenocarcinoma cells derived from the biallelic...


Source: Cancer Weekly (2009-02-03)

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