Cancer Weekly
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Biopsy
Data from University of Virginia provide new insights into biopsy
February 3rd, 2009
"We hypothesized that lymph nodes draining sites of cutaneous vaccination could be identified by sentinel node biopsy techniques, and that measuring T-cell response with lymphocytes obtained from these lymph nodes would provide a more sensitive measure of immunogenicity than would the same measurement made with peripheral blood lymphocytes ( PBL). ELISpot analysis was used to determine the magnitude of vaccine-specific T-cell response in the sentinel immunized nodes ( SIN), random lymph nodes, and peripheral blood lymphocytes ( PBL) obtained from patients enrolled in clinical trials of experimental melanoma vaccines," scientists in the United States report. "The SIN...
Source: Cancer Weekly (2009-02-03)
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