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Cancer Weekly

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Cancer Gene Therapy



Research on cancer gene therapy discussed by scientists at Peking Union Medical College, Biotechnology Department



February 3rd, 2009

Researchers detail in 'MR-1 modulates proliferation and migration of human hepatoma HepG2 cells through myosin light chains-2 (MLC2)/focal adhesion kinase (FAK)/Akt signaling pathway,' new data in cancer gene therapy. According to a study from Beijing, People's Republic of China, "The key of cell migration process on solid substrates is phosphorylation of myosin light chain-2 (MLC2), which is implicated in a variety of intracellular functions. The previous data show that MLC2 interacts with a novel human gene, myofibrillogenesis regulator 1 (MR-1)."

"Here, we reported that MR-1 was specially overexpressed in human hepatoma HepG2 cells. Transient treatment of cells with...


Source: Cancer Weekly (2009-02-03)

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