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Cancer Weekly

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Adenocarcinoma



Researchers from Loyola University report on findings in adenocarcinoma



February 3rd, 2009

"Since clinically significant upgrading of the biopsy Gleason score has an adverse clinical impact, ancillary tools besides the visual determination of primary Gleason pattern are essential to aid in better risk stratification. A total of 61 prostate biopsies were selected in patients with a diagnosis of Gleason score 7 prostatic adenocarcinoma, including 41 with primary Gleason pattern 3 and 20 with primary Gleason pattern 4. Slides from these tissues were stained using Feulgen stain, a nuclear DNA stain," scientists in the United States report.

"Areas of Gleason pattern in all cases were analyzed for 40 nuclear morphometric descriptors of size, shape and chromatin...


Source: Cancer Weekly (2009-02-03)

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