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Cancer Weekly

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Apoptosis



Research in the area of apoptosis reported from Virginia Commonwealth University



February 3rd, 2009

"Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used for the treatment of pain and inflammation. Their use may result in gastroduodenal side effects, such as gastric irritation and ulcer formation," scientists in the United States report.

"Although various strategies have been employed to minimize these adverse effects induced by NSAIDs, effective therapeutic targeting of this problem has been prevented by an incomplete understanding of the mechanisms underlying their pathogenesis. This study was undertaken to determine the role that non-caspase-mediated apoptosis plays in inducing cellular injury and death in gastric mucosa exposed to...


Source: Cancer Weekly (2009-02-03)

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