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Cancer Gene Therapy
Research on cancer gene therapy described by scientists at Virginia Commonwealth University
February 10th, 2009
New research, 'Sp-1 and c-Myc mediate lysophosphatidic acid-induced expression of vascular endothelial growth factor in ovarian cancer cells via a hypoxia-inducible factor-1-independent mechanism,' is the subject of a report. "Lysophosphatidic acid (LPA), which is present in ascites of ovarian cancer patients, stimulates expression of vascular endothelial growth factor (VEGF). VEGF is essential for the development and abdominal dissemination of ovarian cancer," researchers in the United States report. "We examined how LPA drives VEGF expression to gain a better understanding of tumor angiogenesis under normoxic conditions. ELISA, Northern blotting, immunoblotting,...
Source: Cancer Weekly (2009-02-10)
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