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Colon Cancer

Reports from L.C. Chen and co-researchers add new data to research in colon cancer

Published in Cancer Weekly, February 10th, 2009

According to a study from Taiwan, "The pharmacokinetics and internal radionuclide therapy of intraperitoneally administrated Re-188-N,N-bis(2-mercaptoethyl)-N',N'-diethylethylenediamine (BMEDA)-labeled pegylated lipogomal doxorubicin (Re-188-DXR-liposome) were investigated in the C26 murine colon carcinoma ascites mouse model. After intraperitoneal administration of the nanotargeted bimodality Re-188-DXR-liposome, the ascites and tumor accumulation of the radioactivity were observed, the levels of radioactivity within the ascites were maintained at relatively higher levels before 48 h and the levels of radioactivity in the tumor were maintained at steady levels after 4 h. The AUC((o...

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