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Cancer Weekly

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Cancer Gene Therapy



Research on cancer gene therapy reported by C. Lanzi et al



February 10th, 2009

A new study, 'Targeting RET for thyroid cancer therapy,' is now available. According to a study from Milan, Italy, "The limited efficacy of conventional treatments in progressive thyroid carcinomas indicates the need for new therapeutic options. Activating mutations of the receptor tyrosine kinase-encoding RET gene have been identified as driving oncogenic events in subsets of papillary (PTC) and medullary (MTC) thyroid carcinomas suggesting the interest of targeted therapy."

"The role of RET oncogenes and the encoded constitutively active oncoproteins as potential targets has been investigated by different strategies including gene therapy and pharmacological...


Source: Cancer Weekly (2009-02-10)

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