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Cancer Gene Therapy
Researchers from Vanderbilt University, Vanderbilt-Ingram Cancer Center detail findings in cancer gene therapy
February 10th, 2009
Fresh data on cancer gene therapy are presented in the report 'Synergy between phosphatidylinositol 3-kinase/Akt pathway and Bcl-xL in the control of apoptosis in adenocarcinoma cells of the lung.' According to recent research published in the journal Molecular Cancer Therapeutics, "Adenocarcinomas of the lung commonly show an increase in the activity of phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway, yet many are resistant to apoptosis induced by the inhibition of PI3K. We hypothesized that Bcl-xL would have a synergistic effect on the apoptotic response induced by inhibition of the PI3K/Akt pathway in lung adenocarcinoma." "To test this, we examined...
Source: Cancer Weekly (2009-02-10)
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