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Cancer Weekly

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Gene Therapy



Study data from All India Institute of Medical Sciences, Department of Biochemistry provide new insights into gene therapy



February 10th, 2009

Research findings, 'Frequent loss of heterozygosity and altered expression of the candidate tumor suppressor gene 'FAT' in human astrocytic tumors,' are discussed in a new report. According to a study from New Delhi, India, "We had earlier used the comparison of RAPD (Random Amplification of Polymorphic DNA) DNA fingerprinting profiles of tumor and corresponding normal DNA to identify genetic alterations in primary human glial tumors. This has the advantage that DNA fingerprinting identifies the genetic alterations in a manner not biased for locus."

"In this study we used RAPD-PCR to identify novel genomic alterations in the astrocytic tumors of WHO grade II (Low Grade...


Source: Cancer Weekly (2009-02-10)

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