Published in Cancer Weekly, February 10th, 2009
"Functional inhibition of HIF-1 alpha. leads to impaired metastasis formation in murine tumor models. However, the precise molecular mechanisms underlying the metastasis-promoting role of HIF-1 alpha have not been fully characterized. The ability of transformed epithelial cells to initiate the metastatic cascade relies on their ability to escape...
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Source: Cancer Weekly (2009-02-10)
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