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Tissue Engineering

Findings in tissue engineering reported from Lund University

Published in Cancer Weekly, February 10th, 2009

"Macroporous hydrogels (MHs) hold great promise as scaffolds in tissue engineering and cell-based assails. In this study, the possibility of combination of three-dimensional (3D) cell culture with a miniaturized screening format was demonstrated oil human colon cancer HCT116, human acute myeloid leukemia KG-1 cells, and embryonic fibroblasts cultured on MHs (12.5 mm x 7.1 mm I.D.) in a 96-minicolumn plate format," researchers in Lund, Sweden report.

"MHs were prepared by cryogelation technique and functionalized by coating with type I collagen and by copolymerization with agmatine-based mimetic of cell adhesive peptide RGD (abRGDm). Cancer cells formed multicellular...

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