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Cancer Gene Therapy
Research from D.S. Yyu and co-authors provides new data about cancer gene therapy
February 10th, 2009
According to a study from Guangzhou, People's Republic of China, "Previous studies revealed that drug-loaded poly(ethylene-glycol)-poly(gamma-benzyl-L-glutamate) (PEG-PBLG) nanoparticles exhibit favorable pharmacokinetic characteristics in the treatment of oral squamous cell carcinoma (OSCC). In this study, the characteristics and anticancer effect of herpes simplex virus thymidine kinase (HSV-TK)-loaded PEG-PBLG nanoparticles for OSCC were investigated." "HSV-TK-loaded PEG-PBLG nanoparticles were prepared and their morphology, DNA protection and gene-transfer efficiency were evaluated. Their anticancer effect in vitro and in vivo was determined. HSV-TK-loaded PEG-PBLG...
Source: Cancer Weekly (2009-02-10)
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